Martin Short ... Jiminy Glick / David Lynch
Jan Hooks ... Dixie Glick
Linda Cardellini ... Natalie Coolidge
Janeane Garofalo ... Dee Dee
John Michael Higgins ... Andre Devine
Elizabeth Perkins ... Miranda Coolidge
Larry Joe Campbell ... Haygood Lewkin
Mo Collins ... Sharon
DeRay Davis ... Mario 'FA REAL' Greene
Carlos Jacott ... Barry King
Corey Pearson ... Ben DiCarlo
Aries Spears ... Gunnar 'MC GUN' Jorge
Robert Trebor ... Jay Schiffer
Gary Anthony Williams ... Randall Bookerton
Landon Hansen ... Matthew Glick
Jake Hoffman ... Modine Glick
Alex Diakun ... Bellhop / Barber
Peter Breck ... Tibor
Ellie Harvie ... June
Darren Shahlavi ... Johnny Stompanato
Courtney Daniel ... Lana Turner (as Courtney Andersen)
Randi Lynne ... Rowena
Olivia Yung ... Chinese Maid
Ari Solomon ... Rabbi Schleckman
Christine Willes ... Arlene Sheehy
Sue Gillan ... Hotel Clerk (as Susan Gillan)
Peter Kelamis ... Hotel Clerk
Zahf Paroo ... Gandhi's Manager
Allison Warnyca ... Gandhi's Girlfriend
Natasha Wilson ... Sexy Girl
Jano Frandsen ... Award Presenter
Anita Brown ... Award Presenter
Christopher Lazar ... Rap Fan
Sara Willey ... Lana Turner's Daughter
Kiefer Sutherland ... Kiefer Sutherland
Whoopi Goldberg ... Whoppi Goldberg
Kevin Kline ... Kevin Kline
Pat O'Brien ... Self
Sharon Stone ... Sharon Stone
Jake Gyllenhaal ... Jake Gyllenhaal
Forest Whitaker ... Forest Whitaker
Susan Sarandon ... Susan Sarandon
Kurt Russell ... Kurt Russell
Rob Lowe ... Rob Lowe
Steve Martin ... Steve Martin
Kimberley Buchanan ... Gala Girl (uncredited)
Emmanuelle Beart ... Emmanuelle Beart (uncredited)
Kristina Copeland ... Stacee (uncredited)
Willem Dafoe ... Willem Dafoe (uncredited)
Roger Ebert ... Self (uncredited)
David Giammarco ... Hipster Hollywood Actor (uncredited)
Richard Stewart Rigby ... Harvey Weinstein (uncredited)
Chloë Sevigny ... Chloë Sevigny (uncredited)
Celeste White Steele ... Theater Patron (uncredited)